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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425c3d3ffe0dd3a906c83b62bba0e996464e880d13ff4e8cfc8e9fdeada6d4d3' 
  AND token = 'Sawkhcz5C7JNaxyUBmVpu07wP5bXC6VcM0ngvb8u0/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}