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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e56f512c1f4077f772d6836f97cc680b8d846dea208781afe579ab6ce9c1b6' 
  AND token = 'e6TvwLcgNUDS7u7ZiX8E1XHck5janDBTtCCAKs88I5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}