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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cbfcff1ca2bd5ac71aefb6ba50ab6e468304fb663f618fabb63362eba010a0' 
  AND token = 'xkRH2vXAEDkIWtsWUAGb8VwVF9qLKTdXMLCt3gQwD4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}