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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ed11f1fd3f814e80d2b2aeda889be68408fa983f74f0be50093ca3efc196c8f' 
  AND token = 'U8qDwP442tkbjB6/cL+FNVKtLDxdl9oVy2ZjN/JrS5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}