SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac438486f09f6bd1de1123e68078960d697666d3b17a33dd795fa5c6d6924dd' 
  AND token = '+iOGC1lD8vCL8s8dZWEtdR4W3s0/gjrtzkOkb9WvLf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}