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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed70f53186d67388c78e44f6d2e133024a569eb3b522699430cca1dcdaece76' 
  AND token = 'e7ZMd7sKqHBwiwwr6dTvaK6uLS5Xx/3gnxpEHcHIx58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}