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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c68b23816dee930869b050a51ed505c1235a7dc1502e7e81cd58f9050d98c9a' 
  AND token = 'PUefWPPqLgh2wH0Y5CtoK0pw1m0slDY9ZaYuOaD4QAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}