SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f54457164dd934ec42bc3a7d4570acb52dc42a704330415cbee4f96af74dc06' 
  AND token = 'JD8j8BVIDuE1oNgYZgbo3Bo3ey2FivY57xoHvngzq18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}