SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3185033dcd9f4daf2057c009738a601cb5780f97830cfbc3d225c442ba51d0e3' 
  AND token = 'IA3iFkWqHBEoCwrPI4CuG5GmQT5agu4sSTqNNg33OVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}