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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a41a121ae6ce9257f1672242e64b1849927942aa849707ac89d79326dce78fd1' 
  AND token = 'zyyZxeXp+27DLp+GVJfb9vhYvFcbeUwKyO4IdxCCd08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}