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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ace15826cfb9e4d6ffe387cdc3cdc34fc43fd76c4f755da04460a76182654f' 
  AND token = '13C2afLdAF3WeZwdHByWTq2zJHalAtSnLgsOCGhzc7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}