SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f53cb7407f79dcd833943c5c6d82a462f01f78fea82856e9815c49511d9bc000' 
  AND token = 'PST4q9nS267a7j13EkSlVXyVG37us0UgnteQIRRYi1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}