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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c42715e9ade012428d1590583f076addf17696b3b66a26e93f4b285bb7fea153' 
  AND token = '1UWH16Jk4OtyK+I3KtjYnmh2XpUNeRTLozpy787XMOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}