SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ef36f2b7de019db6ec4ae02af8df3c769e46f848fe023d091654cbf49e2b47' 
  AND token = 'Yzsbq4+mn11fqUD4Tb09PlKumJieQAaqQXoRmahN4pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}