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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb7d4cd78e3949a4043c21a1731a90fc1618b4e276ba0b1a0f58af523ef4e290' 
  AND token = 'iTvhJVQP8CvTugX7apW9c8lB7WHKS3mCUherlNU962Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}