SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449887d9011dca14d3691f4309dc0d796aa01804d36b90a9ac9d8636b9328c87' 
  AND token = 'H2Y6C/e+RhD9mICfCQMjPEa5crfl+WyfwCKr15e9gd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}