SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de260fff6c01ec942705667b120a3046e59d31efe3d393c8ac05da73e56bebc2' 
  AND token = 'guTKC/hOuh4K4ADqhuMDZJ1WO11EJnj/zWx2C2RV4rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}