SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '144b0850c63f9c4433aaf8535ba1c142aff9abbadf419f45307945c8e0657ffd' 
  AND token = 'kMf2pBQyGyYL5Am2bJxa1xSjvbyGRT7KzlQIQCGvAlA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}