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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a977d4f33353b6106624608ce59441bc68bb18f83c3153e03d0da08bf670fe5d' 
  AND token = 'C3EtiPWBzCMLFaCoOELjEpE0FsHzKPE92O+3IM/bqAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}