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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d5909f48f0537774d883c8b75f10e5377b1b480891823e9608551b504c0f232' 
  AND token = '//k9xsrwF3/y38nqKJWx79wimgnacrbbWz1BTC65k00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}