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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe654bd57e04c0f79d4a0298cb8a621019ca7ce0366bffd7db35bc5f32f027a1' 
  AND token = '05HV0uz1xaUlJrxSdBfQRAJ+lau+PC2/f8eGbmma2Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}