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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dfbc0b31b4a2f60bd7a258c017c8c3fe0e3c00fb2874c6b14630136e17d2d79' 
  AND token = 'ehOFmXbKYSjyHSyMcXKHy2/ELVVxmuoRSI2Bcv9vmGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}