SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fedf57cd43b1b351526c13b7cfdbbda497e724a5d28cd3a048d43330be7ff29f' 
  AND token = 'XTU0zyFlbXfs0YMN+0wm+fRQ81d+EbTxv1/R4dUErF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}