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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a8878be58d140763c98f76d13919d752b87b61ef057b12054ed6f752b2f6289' 
  AND token = '1x4qspJn2uZl20MZ/4dEZ/vNRQVmshutz4aNdRfnwJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}