SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80edd3ba9347145ab101048492218e955441984dccf09975f04569bb53587037' 
  AND token = 'P5K4K0KMEdxWbEzOSzVb/KiTBrJ/t719GvYJWiSWHjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}