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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08558dda87c9648c0a7746bb9f85bdfd261f9f105f468a8c5d165ec9e13d7325' 
  AND token = 'RPawZBEV0tWZNyk9hbc8jIdHJ+p/qUoL2oL5MN0s6mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}