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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdc2cbd7d1945ebf10cae6f66ee221080ce06342de79f777696561e03bb3088c' 
  AND token = 'jUzjLuY7aGs5zdSuq26IiaqKgj4DdGTZAUfF0AixPOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}