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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de83532d70a78e9d0ccd5a299b91c2aa0171a13e8f1871c3615e8108d55a6cb9' 
  AND token = 'jfHmuOm3VSY72My44i9oz3noVdH1FsfJg67+qMweWmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}