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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be8f1024f98d8085e6285e54faf43569bc7f47d71f07ad846015610c1d91700' 
  AND token = 'sKBWCUtgLOP3u9wbJEmuIo9nb331+g8T5sP9ZFKyOFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}