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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f37353c84d5c2fc3d875b8de8fcec14b3e196560c6564c23a43fe3cdb712303' 
  AND token = 'LJ9Sg5jkRTJ8txcWzWw9pMOwD90oRaBc6h408ZIjKiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}