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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea89e2d23b93cc66cf30bc84a18180dc04a2a5a30f17f9a8831d978cc8a8e26c' 
  AND token = 'MMextTpV6N2BCyA/aauAuaYPM2UladQ+xFUHzjC0w6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}