SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaec682091a69aeb6ee140e5b6f5566274dabd6d177250e8b5d6282e3af2d7cd' 
  AND token = 'Ho/+tyJsPbZ1VZdWkbG79+gOM9Ebw0UffBBVTb810jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}