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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e57cd1ac2d1630d9f796b92e664002e80da98aa3266a064e2fb376a6d6102d' 
  AND token = 'mTmWJ2/Jr/AA7nyB7OskAKt1mtRb3lMuAkhoxsmaSO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}