SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '895153d8c43e6697ea5625f892ea2b7df08f3ed2959ab301e8beda1467271e96' 
  AND token = 'cloNp04dXS/FX2e6RIlLOIXQQlBe79Sn0fY46ra6n04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}