SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f9bef1ea411c9fed61714f0fc835cca7451c0a9f49d605d19fe04c0f045c05f' 
  AND token = 'ksu67nyg6hrCxBUcCbUtrn/eZ/jnXORHQxQU8p0RBoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}