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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4fd779b0cbda4c357bc2746edcda6f9e0193fd2d84551ef6d6359e9541d7b47' 
  AND token = 'X+B9HhcMWOPyh5PaswXeaP+vqUaJS5Yhwe3aw1YXfLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}