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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e727c2a79f465a797ccb557eda741047e2d91745786c852cd6d45ccb31ea8af' 
  AND token = '5chP5wy/f/41xXTaWYTZlWtatMwbnEjk0Zo8ex+w+6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}