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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21bf51d62af22bce8ff217f9211ab2e10561d3064dc1f677266fe7357ced1489' 
  AND token = '6DBAw2rpOK3Jlx3jtB9jiyyXa26o2RHaxppS6H9yKO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}