SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35ca5d459bbcbd2619cde030d2850bcb0b5704e1ee05e1bfa2e067d25f2c4eaa' 
  AND token = '00DvXZREWN7XSvUZanoL4QisBe34Xvz4aN6+NRVL9Iw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}