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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e79b30be084f9d4593f3eb405d0b6d2d70c9cbedb080a0688e491dfcaaa04b' 
  AND token = 'O1pzVT+VWKZ4MnzqU93O9XQ71DlMUk4VVmBc8G2QJ0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}