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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c116a8d715568be66f5670275056aa1189d3f8c9b5a924e32526da8116ef91b2' 
  AND token = 'ZYulS6oVE6D3MkQCr/69inXeJdsOL0UxpPwILl9vzhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}