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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '562e86cb73cd84659fde4aaeab89a6fe3ba420034a36fd2d9f4b84bed58caa47' 
  AND token = 'vFz2prIqAJdGx9lIG523qliFqVucXzDsmL3rmFULwgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}