SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389b5df0e135db76ce6915b99c7fa6a9dffcc92d2106ab50e97fe34a45e91aac' 
  AND token = 'rHJwg5Ne0XgZ/OpMdTCdb4f6mUpD4GYgpP8aBgvV3MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}