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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6facf56a36f15edc1f920d8f34e16a9ea7d253551e990e73f88c8881a0f1ed3' 
  AND token = '54AfpizqXtt7bb44i52XYpddKJGYz3wv3YVfv94ScXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}