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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06726a4c057ae315ce7becff0e5a9f5b374e964e5219b8ccc7ae8199e893748d' 
  AND token = 'kK+Vrd0SGxdq29iAyDUQM1cQoN5fLz+965ejxfpN9Hg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}