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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e210699b435ed67b00df6b729d6acd4773b8e0887b03bfe49fdbb72d49a5b5ca' 
  AND token = 'VkjOS0T5mM1cgzxNEeqFDtcgEXFiuELyt1JmIQx3Iuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}