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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538e72fc97b5a4dcce8640f1e17d5188396e1a7e973d40e4a03f513d4a06afc4' 
  AND token = 'fsS3Xhtsqol8Km/ciQFIePhmcrj30egy8NRnLUaPQvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}