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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e376bbfa1991f516dd3dd4e6121883a208cc9485a5812b4fe9fd7076870728' 
  AND token = 'yMmFiGZMZgXn6feuYMueTns0Gnf8NZMPWQflhZ7d8S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}