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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a946e748660e876f69b461fa440c74b81f0721d98f49c5c86d73a83335d8321' 
  AND token = 'uRnV94Fox1wAiz6orfHY3ytviLSt8Oc1SuF1z2DxQpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}