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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68ea058f00693fbb46a45464be06b73b1a0a3a8177e86b144b1e1775b8edc66b' 
  AND token = 'AitRfpVh2NIEPqHwqbkrCiz2PcfQRNzM+fcQq2PiJoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}